Cannondale Synapse Neo bike 2025

High Performance. Low Profile.
Synapse Neo looks just like it rides: smooth. The quiet Bosch Performance Line SX drive unit is neatly integrated into the carbon frame, and premium componentry like our Conceal Stem, HollowGram carbon wheels, and electronic shifting keep things clean, quick, and reliable.

Easy Rider
The light but mighty Bosch Performance Line SX drive unit provides support up to higher cadences for a natural pedaling feel. It’s powered by a 400Wh battery and brings a smooth, powerful boost up to 25km/h, then seamlessly disengages for effortless pedaling at greater speeds.

The Real Deal
True road bike performance comes standard here. Based on the comfortable endurance geometry of our pro-level Synapse, Synapse Neo provides the same precise handling, confident control, and incredibly smooth ride as that award-winning machine.

Masterful Material
Based on our non-electric Synapse endurance race bike and rendered in our refined Series 2 carbon fiber construction, the Synapse Neo frameset achieves low weight and superlative performance.

Effortless Interface
The Bosch Kiox 500 display on the handlebar is easy to read and use, giving you full control over the drive system, and can even work in conjunction with the Bosch Flow app for more convenience.

Proper Stoppers
Huge descents, high speeds, wet weather: the powerful hydraulic disc brakes can handle it all and bring you to a stop with cool, confident control.

Race-Ready Rubber
Vittoria Corsa tires are professional-grade racing tires and you’ll find them on Synapse Neo. The wide 30mm version used here means enhanced smoothness and control, and you have clearance for up to 45mm tires if you want to go bigger.

Ready to Roam
When you don't want the ride to end, it doesn’t have to. An optional secondary battery can be installed in minutes and adds 250Wh. That means going farther and pushing higher, while still getting home easily.

Versatility Built In
Every Synapse Neo comes with mounts for fenders, a kickstand, and a rear rack, making it easy to set the bike up for poor weather and greater utility.

Fits Like a Glove
Our Proportional Response approach means that every Synapse Neo is engineered for consistent performance across the size range. From the biggest to the smallest, every rider gets the same ride quality, handling, and responsiveness.


Tech spec

  • Frame: Synapse Neo Carbon, internal downtube battery, integrated cable routing, 148mm dropout spacing, 12mm thru-axle, SAVE, flat mount disc, removable kickstand mount (40mm Pletscher-style)
  • Fork: Synapse Neo Carbon, 1-1/8" to 1.5" Delta steerer, flat mount disc, internal routing, 12x110 thru-axle
  • Rims: HollowGram R 45, Carbon, 24h front, 28h rear, 50mm deep, 21mm inner width, tubeless ready
  • Hubs: (F) HollowGram, sealed bearing 12x110mm centerlock / (R) HollowGram 3-pawl, sealed bearing, 12x148mm centerlock
  • Spokes: Stainless Steel, 14g
  • Tires: Vittoria Corsa, 700x30c
  • Crank: FSA Bosch E-Bike, 50/34
  • Chain: Shimano Ultegra, 12-speed
  • Rear Cogs: Shimano Ultegra, 11-34, 12-speed
  • Front Derailleur: Shimano Ultegra Di2 8150, braze-on
  • Rear Derailleur: Shimano Ultegra Di2 R8150, 12-speed
  • Shifters: Shimano Ultegra Di2 8150, 12-speed
  • Handlebar: Vision Metron Aero carbon, 31.8
  • Grips: Fabric Knurl tape, 3mm
  • Stem: Cannondale C1 Conceal, Alloy, 31.8, -6°
  • Headset: Integrated, 1-1/8" - 1.5"
  • Brakes: Shimano Ultegra Di2 hydraulic disc, 160/160mm MT800 rotors
  • Brake Levers: Shimano Ultegra Di2 hydraulic disc
  • E-Bike Display: Bosch Kiox 500
  • E-Bike Battery: Bosch Compact Powertube 400Wh
  • E-Bike Charger: Bosch 2A
  • E-Bike Drive Unit: Bosch Performance Line SX, 25 km/h
  • Saddle: Fizik Tempo Argo R5, 150mm width, S-alloy rails
  • Seatpost: Cannondale 1, SAVE, UD Carbon, 25.4x350mm (XS-S), 400mm (M-XL)
  • Speeds: 24

Manufacturer's notes: depending on component availability, specifications are subject to change without notice.